The authors of a recent review assert that all diet-related chronic diseases are linked to the microbiome but there is limited consideration of these interactions in contemporary dietary guidelines.
Research illustrates the commonalities between microbiome and nutritional disciplines in relation to diseases, physiological states, and experimental approaches, they write.
This offers “clear testament to the profound effects of diet on human health” and is further demonstrated by the
escalation of chronic diseases in non-industrialised populations that transition to a Western-style diet, they
say.
The reviewers therefore propose microbiome-targeted nutritional strategies and an experimental framework
for “systematic incorporation of the gut microbiome into future nutrition research”.
“We apply this knowledge to inform discussions of nutrition controversies and advance innovative dietary strategies.”
Scientific rational
The comprehensive review, published in Cell Host & Microbe, discusses national dietary guidelines from a
microbiome perspective and evidence that demonstrates interactions between host gut microbiome, diet, and
physiological mechanisms.
A healthy diet is crucial for disease management and in controlling levels of non-communicable chronic
diseases. Microbes in the gastrointestinal tract contribute significantly to the proper functioning of host
metabolism and immunology.
